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Thrombomodulin alfa - Asahi Kasei Pharma Corp

Drug Profile

Thrombomodulin alfa - Asahi Kasei Pharma Corp

Alternative Names: ART-123; AT 908; Human recombinant thrombomodulin - Asahi Kasei Pharma Corp; Recombinant human soluble thrombomodulin - Asahi Kasei Pharma Corp; Recombinant thrombomodulin alfa - Asahi Kasei Pharma Corp; Recombinant thrombomodulin alpha - Asahi Kasei Pharma Corp; Recomodulin; Recomodulin® anticoagulant intravenous infusion 12800; rhs-TM - Asahi Kasei Pharma Corp; Thrombomodulin alpha - Asahi Kasei Pharma Corp; TMD-123

Latest Information Update: 17 Mar 2021

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At a glance

  • Originator Asahi Kasei; Asahi Kasei Pharma Corp
  • Developer Asahi Kasei; Asahi Kasei Pharma America Corp; Asahi Kasei Pharma Corp
  • Class Anti-inflammatories; Anticoagulants; Antifibrotics; Antithrombotics; Peptides; Platelet membrane glycoproteins; Recombinant proteins
  • Mechanism of Action Protein C stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Disseminated intravascular coagulation
  • Phase II Peripheral nervous system diseases
  • Discontinued Deep vein thrombosis; Idiopathic pulmonary fibrosis

Most Recent Events

  • 16 Mar 2021 Phase III development is ongoing in Disseminated intravascular coagulation in sepsis (severe sepsis with coagulopathy) outside Japan (IV) (Asahi Kasei Pharma Corp website, March 2021)
  • 16 Mar 2021 Phase-II clinical development is ongoing in Peripheral nervous system diseases (Chemotherapy-induced) in Japan (IV) (Asahi Kasei Pharma Corp pipeline, March 2021)
  • 31 Jul 2020 Asahi Kasei Pharma America Corporation plans a phase II trial for Peripheral neuropathies (chemotherapy induced) in November 2020 (NCT04492436)
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