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Thrombomodulin alfa - Asahi Kasei Pharma

Drug Profile

Thrombomodulin alfa - Asahi Kasei Pharma

Alternative Names: ART-123; AT 908; Human recombinant thrombomodulin - Asahi Kasei Pharma; Recombinant human soluble thrombomodulin - Asahi Kasei Pharma; Recombinant thrombomodulin alfa - Asahi Kasei Pharma; Recombinant thrombomodulin alpha - Asahi Kasei Pharma; Recomodulin; Recomodulin® anticoagulant intravenous infusion 12800; rhs-TM - Asahi Kasei Pharma; Thrombomodulin alpha - Asahi Kasei Pharma; TMD-123

Latest Information Update: 29 Jan 2019

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At a glance

  • Originator Asahi Kasei; Asahi Kasei Pharma Corp
  • Developer Asahi Kasei; Asahi Kasei Pharma America Corp; Asahi Kasei Pharma Corp
  • Class Anti-inflammatories; Anticoagulants; Antithrombotics; Peptides; Platelet membrane glycoproteins; Recombinant proteins
  • Mechanism of Action Protein C stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Disseminated intravascular coagulation
  • Phase III Idiopathic pulmonary fibrosis
  • No development reported Deep vein thrombosis

Most Recent Events

  • 31 Dec 2018 Asahi Kasei Pharma Corporation completes a phase III trial in Idiopathic pulmonary fibrosis in Japan (NCT02739165)
  • 19 Oct 2018 Efficacy and adverse events data from a phase II trial in prevention of treatment-related symptoms in Colon cancer presented at the 43rd European Society for Medical Oncology Congress (ESMO-2018)
  • 02 Aug 2018 Preliminary efficacy and pharmacodynamics data from the phase III SCARLET trial in Disseminated intravascular coagulation released by Asahi Kasei Pharma America Corp
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