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Thrombomodulin alfa - Asahi Kasei Pharma

Drug Profile

Thrombomodulin alfa - Asahi Kasei Pharma

Alternative Names: ART-123; AT 908; Human recombinant thrombomodulin - Asahi Kasei Pharma; Recombinant human soluble thrombomodulin - Asahi Kasei Pharma; Recombinant thrombomodulin alfa - Asahi Kasei Pharma; Recombinant thrombomodulin alpha - Asahi Kasei Pharma; Recomodulin; Recomodulin® anticoagulant intravenous infusion 12800; rhs-TM - Asahi Kasei Pharma; Thrombomodulin alpha - Asahi Kasei Pharma; TMD-123

Latest Information Update: 10 Jul 2019

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At a glance

  • Originator Asahi Kasei; Asahi Kasei Pharma Corp
  • Developer Asahi Kasei; Asahi Kasei Pharma America Corp; Asahi Kasei Pharma Corp
  • Class Anti-inflammatories; Anticoagulants; Antithrombotics; Peptides; Platelet membrane glycoproteins; Recombinant proteins
  • Mechanism of Action Protein C stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Disseminated intravascular coagulation
  • Phase III Idiopathic pulmonary fibrosis
  • Phase II Peripheral nervous system diseases
  • No development reported Deep vein thrombosis

Most Recent Events

  • 10 Jul 2019 No development reported - Phase-II for Disseminated intravascular coagulation (In adolescents, In children, In infants) in Japan (IV)
  • 14 Jun 2019 Asahi Kasei Pharma America Corporation completes a phase III trial in Disseminated intravascular coagulation in USA, Australia, Canada, Argentina, Brazil, Bulgaria, Colombia, Croatia, Czech Republic, Finland, France, Germany, Hungary, India, Israel, Netherlands, New Zealand, Peru, Serbia, Spain and United Kingdom (NCT01598831)
  • 12 Jun 2019 Asahi Kasei Pharma America Corporation withdraws the SCARLET2 phase III trial in Disseminated intravascular cogaulation in USA since the sponsor decided to change the design based on previous study's results (700295552 (NCT03517501)
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