Tenofovir disoproxil fumarate - Gilead Sciences

Drug Profile

Tenofovir disoproxil fumarate - Gilead Sciences

Alternative Names: Bis-POC-PMPA; GSK548470; PMPA-prodrug; Tenofovir DF; Tenozet; Viread

Latest Information Update: 16 May 2018

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At a glance

  • Originator Institute of Organic Chemistry and Biochemistry (Prague); Rega Institute for Medical Research
  • Developer Gilead Sciences; GlaxoSmithKline
  • Class Antiretrovirals; Phosphonic acids; Purines; Small molecules
  • Mechanism of Action Nucleotide reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Hepatitis B; HIV infections

Most Recent Events

  • 11 Apr 2018 Efficacy data from a phase III trial in Hepatitis B presented at the The International Liver Congress (ILC-2018)
  • 04 Mar 2018 Efficacy data from a pooled analysis of two phase III trials in Hepatitis B presented at the 25th Conference on Retroviruses and Opportunistic Infections (CROI-2018)
  • 16 Aug 2017 Gilead Sciences completes a phase III trial for HIV-1 infections (In children, Combination therapy) in USA, Panama, Puerto Rico, United Kingdom (PO) (NCT00528957)
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