Drug Profile
Estradiol topical - Orion
Alternative Names: Divigel; Estradiol gel - Orion; Estradiol hemihydrate; Gynpolar; Sandrena; Sisare Gel MonoLatest Information Update: 19 Dec 2021
Price :
$50
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At a glance
- Originator Orion
- Developer Merck & Co; POLA PHARMA; Teva Canada; Vertical Pharmaceuticals
- Class Antineoplastics; Estradiol congeners; Estrenes; Hormonal replacements; Small molecules
- Mechanism of Action Estrogen receptor agonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Marketed Postmenopausal osteoporosis; Vasomotor symptoms
Most Recent Events
- 28 Nov 2018 Searchlight Pharma acquires commercial rights to estradiol topical (Divigel®) in Canada
- 24 Mar 2014 Vertical Pharmaceuticals acquires estradiol topical from Upsher-Smith in USA
- 30 Jun 2009 Final efficacy and adverse events data from a phase III trial in Vasomotor symptoms released by Upsher-Smith Laboratories