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Pralnacasan

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Drug Profile

Pralnacasan

Alternative Names: HMR 3480; VX 740

Latest Information Update: 18 Aug 2009

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At a glance

  • Originator Vertex Pharmaceuticals
  • Class Anti-inflammatories; Antirheumatics; Azepines; Isoquinolines; Pyridazines; Small molecules
  • Mechanism of Action Caspase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • Discontinued Inflammation; Inflammatory bowel diseases; Osteoarthritis; Psoriasis; Rheumatoid arthritis

Most Recent Events

  • 31 Dec 2005 Phase-II clinical trials resumed in Rheumatoid arthritis in Canada (PO)
  • 31 Dec 2005 Phase-II clinical trials resumed in Rheumatoid arthritis in USA (PO)
  • 11 Mar 2005 Suspended - Phase-II for Osteoarthritis in USA (PO)

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