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TG 1042

Drug Profile

TG 1042

Alternative Names: Ad-IFNγ; Adenovirus interferon gamma; ASN 002 - Ascend; TG-1042

Latest Information Update: 19 Jun 2018

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At a glance

  • Originator Transgene
  • Developer Ascend Biopharmaceuticals; Nantes University Hospital; Transgene
  • Class Antineoplastics; Gene therapies; Immunotherapies; Interferons
  • Mechanism of Action Gene transference; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T-cell lymphoma; Basal cell nevus syndrome
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Basal cell cancer
  • No development reported Malignant melanoma
  • Discontinued Cutaneous B-cell lymphoma; Cutaneous T-cell lymphoma

Most Recent Events

  • 03 Jun 2018 Ascend Biopharmaceuticals suspends a phase I/II trial as another protocol is being developed in Basal cell cancer in USA (Intratumoural) (NCT03208296)
  • 14 Dec 2017 Ascend Biopharmaceuticals completes a phase I/II trial in Basal cell cancer in Australia (Intratumoural) (NCT02550678)
  • 14 Dec 2017 Adverse events and efficacy data from a phase I/II trial in Basal cell cancer released by Ascend Biopharmaceuticals
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