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HIF-1 alpha gene therapy - Sanofi Genzyme

Drug Profile

HIF-1 alpha gene therapy - Sanofi Genzyme

Alternative Names: Ad2/HIF-1 alpha; Ad2/HIF-1a; Ad2/HIF-1α/VP16; Cardiovascular disease gene therapy - Sanofi Genzyme

Latest Information Update: 21 Dec 2016

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At a glance

  • Originator Johns Hopkins University
  • Developer Genzyme Corporation
  • Class Gene therapies; Peripheral vasodilators
  • Mechanism of Action Angiogenesis inducing agents; Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • No development reported Intermittent claudication; Peripheral arterial disorders
  • Discontinued Ischaemic heart disorders

Most Recent Events

  • 31 Mar 2012 No development reported - Phase-II for Intermittent claudication in European Union (IM)
  • 31 Mar 2012 No development reported - Phase-II for Intermittent claudication in USA (IM)
  • 31 Mar 2012 No development reported - Phase-II for Peripheral arterial disorders in European Union (IM)
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