Drug Profile


Alternative Names: DF-1681Y; Repertaxin; Repertaxin L-Lysine salt

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Dompe Farmaceutici
  • Developer Dompe Farmaceutici; Fox Chase Cancer Center; SatRx; University of Michigan Comprehensive Cancer Center
  • Class Antineoplastics; Benzeneacetamides; Small molecules; Sulfonamides
  • Mechanism of Action Interleukin 8A receptor antagonists; Interleukin 8B receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Delayed graft function
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Delayed graft function
  • Phase II Breast cancer; Liver transplant rejection
  • Discontinued Cerebral ischaemia

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Breast-cancer(Combination therapy, Metastatic disease, Second-line therapy or greater) in USA (PO, Tablet)
  • 28 Oct 2016 Phase-II clinical trials in Delayed graft function (Prevention) in Russia (IV) before October 2016 (Dompé pipeline, October 2016)
  • 28 Oct 2016 Dompé Farmaceutici and SatRx plan a phase II/III trial for Delayed graft function in liver transplant patients in Russia (Dompé website, October 2016)
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