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Mepolizumab - GlaxoSmithKline

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Drug Profile

Mepolizumab - GlaxoSmithKline

Alternative Names: 240563; Bosatria; Mepolizamab; Nucala; SB-240563

Latest Information Update: 07 Jan 2025

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At a glance

  • Originator GlaxoSmithKline
  • Developer GlaxoSmithKline; GSK; McMaster University; National Institute of Allergy and Infectious Diseases
  • Class Anti-inflammatories; Antiallergics; Antiasthmatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interleukin 5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypereosinophilic syndrome; Churg-Strauss syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Asthma; Nasal polyps
  • Registered Churg-Strauss syndrome; Hypereosinophilic syndrome
  • Preregistration Chronic obstructive pulmonary disease
  • Phase II Eosinophilic oesophagitis
  • Discontinued Atopic dermatitis

Most Recent Events

  • 03 Jan 2025 Registered for Asthma (In adults, In adolescents, Adjunctive treatment) in China (SC) prior to January 2025
  • 03 Jan 2025 Registered for Churg-Strauss syndrome (Adjunctive treatment, In adults) in China (SC) prior to January 2025
  • 03 Jan 2025 Registered for Nasal polyps in China (SC)

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