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Mepolizumab - GlaxoSmithKline

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Drug Profile

Mepolizumab - GlaxoSmithKline

Alternative Names: 240563; Bosatria; Mepolizamab; Nucala; SB-240563

Latest Information Update: 24 Mar 2026

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At a glance

  • Originator GlaxoSmithKline
  • Developer GlaxoSmithKline; GSK; McMaster University; National Institute of Allergy and Infectious Diseases
  • Class Anti-inflammatories; Antiallergics; Antiasthmatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interleukin 5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypereosinophilic syndrome; Churg-Strauss syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Asthma; Nasal polyps
  • Registered Chronic obstructive pulmonary disease; Churg-Strauss syndrome; Hypereosinophilic syndrome
  • Phase II Eosinophilic oesophagitis
  • Discontinued Atopic dermatitis

Most Recent Events

  • 06 Feb 2026 Registered for Chronic obstructive pulmonary disease (Adjunctive treatment) in European Union, Liechtenstein, Iceland, Norway (SC)
  • 05 Jan 2026 Registered for Chronic obstructive pulmonary disease (Adjunctive treatment) in China (SC)
  • 31 Dec 2025 Registered for Chronic obstructive pulmonary disease (Adjunctive treatment) in United Kingdom (SC), in fourth quarter of 2025

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