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Botulinum toxin A - Ipsen

Drug Profile

Botulinum toxin A - Ipsen

Alternative Names: AbobotulinumtoxinA; Azzalure; BoNT-A; BTX-A-HAC; BTX-A-HAC NG; Clostridium botulinum toxin type A haemagglutinin complex; Dysport; DYSPORT AESTHETIC; Dysport NG; Dysport RU; Dysport Solution; Dysport® Next Generation; Reloxin

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Health Protection Agency Porton Down; Ipsen Limited
  • Developer Biosintetica; Galderma; Ipsen Limited; Medicis Pharmaceutical Corporation; Valeant Pharmaceuticals International
  • Class Analgesics; Antidepressants; Antimigraines; Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Eye disorder therapies; Muscle relaxants; Skin disorder therapies; Urologics
  • Mechanism of Action Acetylcholine inhibitors; Glutamate-antagonists; Membrane transport protein modulators; Neuromuscular blocking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Torticollis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Blepharospasm; Equinus foot deformity; Facial-wrinkles; Fissure in ano; Glabellar lines; Hyperhidrosis; Muscle spasticity; Neurogenic bladder; Spasm; Torticollis
  • Phase III Musculoskeletal disorders; Overactive bladder; Urinary incontinence
  • Phase II Gilles de la Tourette's syndrome; Hallux valgus; Vulvodynia
  • Discontinued Pain

Most Recent Events

  • 17 Sep 2018 Preregistration for Glabellar lines in China (IM) (Ipsen pipeline, September 2018)
  • 10 Sep 2018 Ipsen plans the RESPITE phase II trial for Pain in United Kingdom in September 2018 (NCT03663101)
  • 04 Sep 2018 Ipsen completes the phase III PUL trial in Muscle spasticity (spasticity of upper limbs, in children with cerebral palsy) (In adolescents) in Belgium, Czech Republic, Israel, Mexico, Poland, Spain, Turkey and USA (IM) (NCT02106351)
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