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Arzoxifene

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Drug Profile

Arzoxifene

Alternative Names: Arzoxifene hydrochloride; LY353381; SERM III; SERM-3

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Eli Lilly and Company
  • Class Antineoplastics; Osteoporosis therapies; Piperidines; Thiophenes
  • Mechanism of Action Selective estrogen receptor agonists; Selective estrogen receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Breast cancer; Endometrial cancer; Ovarian cancer; Peritoneal cancer; Postmenopausal osteoporosis

Most Recent Events

  • 15 Sep 2009 Efficacy data from a phase III trial in postmenopausal osteoporosis presented at the 31st Annual Meeting of the American Society for Bone and Mineral Research (ASBMR-2009)
  • 25 Mar 2009 Efficacy and safety data from the phase III, NEXT trial in Postmenopausal osteoporosis released by Eli Lilly
  • 11 Dec 2007 Clinical development is ongoing

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