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Bupivacaine extended release - Pacira BioSciences

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Drug Profile

Bupivacaine extended release - Pacira BioSciences

Alternative Names: Bupivacaine extended-release - Pacira BioSciences; Bupivacaine extended-release liposome injection; Bupivacaine liposome extended-release injectable suspension; Bupivacaine liposome injectable suspension; DepoBupivacaine; Exparel; SKY-0402

Latest Information Update: 02 Dec 2025

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At a glance

  • Originator SkyePharma Inc
  • Developer Nuance Biotech; Pacira BioSciences; Pacira Pharmaceuticals
  • Class Amides; Analgesics; Anilides; Anti-inflammatories; Local anaesthetics; Non-opioid analgesics; Piperidines; Small molecules; Xylenes
  • Mechanism of Action Sodium channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Anaesthesia; Postoperative pain
  • Phase III Dental pain
  • No development reported Musculoskeletal pain; Pain

Most Recent Events

  • 26 Nov 2025 Pacira BioSciences initiates litigation against The WhiteOak Group, Inc. and Qilu Pharmaceutical (Hainan) over ANDA submission in the US
  • 31 Aug 2025 Pacira BioSciences has patent protection for "composition of EXPAREL manufactured by an enhanced process from our large-scale batch process" in the US
  • 05 Aug 2025 Pacira BioSciences has patent protection for EXPAREL in USA

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