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Certolizumab pegol - UCB

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Drug Profile

Certolizumab pegol - UCB

Alternative Names: AutoClicks-Prefilled-Pen; CDP-870; Certolizumab; Cimzia; CIMZIA AutoClicks Prefilled Pen; Cimzia AutoClicks Prefilled Pen; CZP; PHA-738144; Simziya

Latest Information Update: 27 Jun 2025

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At a glance

  • Originator UCB
  • Developer Astellas Pharma; UCB; University of Pennsylvania; University of Southampton; University of Washington
  • Class Anti-inflammatories; Antipsoriatics; Antirheumatics; Fab fragments; Monoclonal antibodies; Nootropics; Polyethylene glycols
  • Mechanism of Action Immunosuppressants; Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Ankylosing spondylitis; Axial spondyloarthritis; Crohn's disease; Plaque psoriasis; Psoriatic arthritis; Rheumatoid arthritis
  • Registered Non-radiographic axial spondyloarthritis
  • Phase III Interstitial cystitis; Juvenile rheumatoid arthritis
  • Phase II Ulcerative colitis
  • Discontinued Cognition disorders

Most Recent Events

  • 11 Jun 2025 An expanded access trial for Crohn's disease is no longer available (NCT03559660)
  • 18 Jun 2024 UCB Pharma initiates the phase III REALISTIC trial in Rheumatoid arthritis in USA, Canada, Germany, Netherlands (SC) (NCT00717236)
  • 28 Mar 2024 UCB completes the phase III PASCAL trial in Juvenile rheumatoid arthritis in USA, Canada, Argentina, Brazil, Chile, Mexico and Russia (NCT01550003) (EudraCT2009-018027-33)

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