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Acotiamide - Zeria/Astellas Pharma

Drug Profile

Acotiamide - Zeria/Astellas Pharma

Alternative Names: Acofide; Acotiamide hydrochloride hydrate; YM 443; Z-338

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Zeria
  • Developer Astellas Pharma; Zeria
  • Class Benzamides; Gastrokinetics; Small molecules; Thiazoles
  • Mechanism of Action Acetylcholine stimulants; Acetylcholinesterase inhibitors; Muscarinic M1 receptor antagonists; Muscarinic M2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Non-ulcer dyspepsia
  • Phase II Helicobacter infections

Most Recent Events

  • 22 Feb 2018 Astellas Pharma and Zeria Pharmaceutical completes a phase II trial for Non-ulcer dyspepsia and Helicobacter infections in Japan (UMIN000023886)
  • 01 Apr 2017 Zeria Pharmaceutical completes a phase III trial in Non-ulcer dyspepsia in Belgium, Bulgaria, Latvia, Lithuania, Romania, Russia, Slovakia, Sweden, Ukraine, United Kingdom (NCT01973790)
  • 13 Feb 2017 Acotiamide is still in phase-II development for Non-ulcer dyspepsia in USA (PO) (Zeria pipeline, February 2017)
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