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DTI 015

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Drug Profile

DTI 015

Alternative Names: BCNU - Direct Therapeutics; Carmustine - Direct Therapeutics; Injectable carmustine - Direct Therapeutics

Latest Information Update: 21 Oct 2021

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At a glance

  • Originator Direct Therapeutics
  • Class Antineoplastics; Nitrosourea compounds
  • Mechanism of Action Alkylating agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Glioblastoma; Liver cancer

Most Recent Events

  • 26 Apr 2007 Discontinued - Phase-I for Liver cancer in USA (Intratumoural)
  • 26 Apr 2007 Discontinued - Phase-II for Glioblastoma in USA (Intratumoural)
  • 24 Oct 2002 Approval to begin a new European study of DTI 015 in patients with newly diagnosed high-grade glioma has been granted by the United Kingdom's Medicines Control Agency

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