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Tebipenem pivoxil - Spero Therapeutics

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Drug Profile

Tebipenem pivoxil - Spero Therapeutics

Alternative Names: GSK-3778712; L-084; ME1211; Orapenem; SPR-994; TBP-PI-HBr; TBPM-PI-HBr; Tebipenem; Tebipenem HBr; Tebipenem pivoxil hydrobromide; Tebipenem-prodrug

Latest Information Update: 10 Jan 2024

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At a glance

  • Originator Wyeth K.K.
  • Developer GSK; Meiji Seika Pharma; Spero Therapeutics; Wyeth K.K.
  • Class Anti-infectives; Anti-inflammatories; Antibacterials; Azabicyclo compounds; Azetidines; Carbapenems; Esters; Small molecules; Thiazoles
  • Mechanism of Action Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Haemophilus infections; Streptococcal infections
  • Preregistration Pyelonephritis; Urinary tract infections
  • Phase II Shigella infections
  • No development reported Unspecified

Most Recent Events

  • 02 Jan 2024 Phase-III clinical trials in Pyelonephritis (PO) (NCT06059846) (EudraCT2023-503785-22-00)
  • 02 Jan 2024 Phase-III clinical trials in Urinary tract infections (Complicated) (PO) (NCT06059846) (EudraCT2023-503785-22-00)
  • 02 Jan 2024 Spero Therapeutics initiates enrolment in the phase-III PIVOT-PO trial for Urinary tract infections (Complicated) and Pyelonephritis at an unknown location (NCT06059846)
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