HE 2000

Drug Profile

HE 2000

Alternative Names: 16-Bromoepiandrosterone; Alpha-Epi-Br (HE2000) - Harbor BioSciences; Immunitin; Inactivin

Latest Information Update: 21 Feb 2012

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At a glance

  • Originator Colthurst
  • Developer Cystic Fibrosis Foundation Therapeutics; Harbor Therapeutics; Hollis-Eden Pharmaceuticals
  • Class Androstanols; Antivirals; Small molecules
  • Mechanism of Action Enzyme inhibitors; HIV replication inhibitors; Immunomodulators; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Suspended Hepatitis B; Hepatitis C; HIV infections; Malaria; Tuberculosis
  • Discontinued Cystic fibrosis

Most Recent Events

  • 18 Jan 2011 HE 2000 licensed to China State Institute of Pharmaceutical Industry in China and Hong Kong
  • 06 Aug 2007 Suspended - Phase-II for Hepatitis B in Malaysia (unspecified route)
  • 06 Aug 2007 Suspended - Phase-II for Hepatitis B in Singapore (unspecified route)
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