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NOX 100

Drug Profile

NOX 100

Alternative Names: Norathiol; NOX-100

Latest Information Update: 18 Jan 2016

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At a glance

  • Originator Medinox
  • Developer Medinox; Orient Europharma
  • Class Free radicals; Nitrogen oxides; Small molecules; Vascular disorder therapies
  • Mechanism of Action Nitric oxide inhibitors; NMDA receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Intradialytic hypotension
  • Phase I/II Septic shock
  • Discontinued Acute lung injury; Adult respiratory distress syndrome; Transplant rejection

Most Recent Events

  • 01 Jul 2015 Medinox and Orient Europharma completes a phase II trial in Intradialytic hypotension in Taiwan (IV) (NCT01672008)
  • 08 Jun 2015 Phase-I/II clinical development is ongoing for septic shock, and phase-II development is ongoing for intradialytic hypotension
  • 02 Apr 2014 NOX 100 is still in phase IIa trials for Intradialytic hypotension in Taiwan
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