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NOX 100

Drug Profile

NOX 100

Alternative Names: Norathiol; NOX-100

Latest Information Update: 03 Oct 2019

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At a glance

  • Originator Medinox
  • Developer Medinox; Orient Europharma
  • Class Free radicals; Hexanols; Small molecules; Thiocarbamates; Vascular disorder therapies
  • Mechanism of Action Nitric oxide inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Intradialytic hypotension; Septic shock
  • Discontinued Acute lung injury; Adult respiratory distress syndrome; Transplant rejection

Most Recent Events

  • 03 Oct 2019 Chemical structure information added
  • 01 Jul 2015 Medinox and Orient Europharma completes a phase II trial in Intradialytic hypotension in Taiwan (IV) (NCT01672008)
  • 08 Jun 2015 Phase-I/II clinical development is ongoing for septic shock, and phase-II development is ongoing for intradialytic hypotension
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