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Drug Profile


Alternative Names: R 848; S 28463; VML 600

Latest Information Update: 21 Dec 2015

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At a glance

  • Originator 3M Pharmaceuticals
  • Developer Spirig Pharma
  • Class Adjuvants; Antineoplastics; Antivirals; Imidazoles; Quinolones; Skin disorder therapies; Small molecules
  • Mechanism of Action Immunostimulants; Interferon alpha stimulants; Toll-like receptor 7 agonists; Toll-like receptor 8 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Actinic keratosis; Basal cell cancer; Hepatitis C; Herpes simplex virus infections; Immunological disorders

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 24 Oct 2013 Spirig Pharma discontinues a phase II trial in Basal cell carcinoma in Germany (NCT01808950)
  • 04 Sep 2013 Spirig Pharma discontinues a phase II trial in Actinic keratosis in Germany and Switzerland (NCT01806961)
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