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Drug Profile


Alternative Names: MEN 11420

Latest Information Update: 28 Jul 2017

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At a glance

  • Originator Menarini
  • Class Antiasthmatics; Antispasmodics; Cyclic peptides; Irritable bowel syndrome therapies
  • Mechanism of Action Neurokinin 2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Asthma; Colic; Gastrointestinal disorders; Postoperative ileus

Most Recent Events

  • 28 Jul 2017 Discontinued - Phase-II for Colic (In infants) in USA, Sweden, Poland, Germany, and Italy (PO), because Nepadutant was not listed on Menarini pipeline, July 2017
  • 02 Jun 2015 Phase II development in Colic (infants) is ongoing in USA, Sweden, Poland, Germany and Italy
  • 15 Nov 2010 Phase-II clinical trials in Colic in infants in Sweden (unspecified route)
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