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Vinflunine - Pierre Fabre

Drug Profile

Vinflunine - Pierre Fabre

Alternative Names: F-12158; Javlor; L-0070; Vinflunine ditartrate

Latest Information Update: 18 Feb 2019

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At a glance

  • Originator Pierre Fabre
  • Class Antineoplastics; Vinca alkaloids
  • Mechanism of Action Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Bladder cancer
  • Preregistration Breast cancer
  • Phase III Head and neck cancer; Urogenital cancer
  • No development reported Mesothelioma; Non-small cell lung cancer; Solid tumours
  • Discontinued Gastric cancer; Ovarian cancer

Most Recent Events

  • 23 Nov 2018 Pierre Fabre Medicament completes a phase III trial in Head and neck cancer (Combination therapy, Locally recurrent, Metastatic disease, Second-line therapy or greater) in Austria, Belgium, Estonia, Germany, Poland, Slovakia, Spain, France and Italy (IV) (NCT02347332) (EudraCT2011-005081-38)
  • 24 Jun 2018 Biomarkers information updated
  • 01 Jul 2017 Pierre Fabre completes a phase III trial in Breast cancer (Combination therapy, Locally recurrent, Metastatic disease, Second-line therapy or greater, Late-stage disease) in Taiwan, China, Singapore (IV) (NCT01953003)
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