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Drug Profile


Alternative Names: BAY 59-8862; IDN 5109; SBT 101131

Latest Information Update: 20 Jul 2017

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At a glance

  • Originator Indena; State University of New York
  • Developer Indena; Spectrum Pharmaceuticals
  • Class Antineoplastics; Polycyclic bridged compounds; Taxanes
  • Mechanism of Action P-glycoprotein inhibitors; Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Solid tumours
  • Discontinued Non-Hodgkin's lymphoma; Renal cell carcinoma

Most Recent Events

  • 20 Jul 2017 Ortataxel is still at phase II development stage for Solid tumours in USA (PO) (IV) (Spectrum Pharmaceuticals website, July 2017)
  • 09 Jun 2015 Ortataxel is still in phase II for Solid tumours in USA (PO, IV)
  • 09 Jun 2015 Ortataxel is available for licensing in Europe, Asia (excluding USA) - http://www.sppirx.com/340-spectrum-products-out-licensing.html
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