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IC 14

Drug Profile

IC 14

Alternative Names: Anti-CD14 antibody

Latest Information Update: 10 Apr 2018

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At a glance

  • Originator ICOS Corporation
  • Developer ICOS Corporation; Implicit Bioscience; University of Washington
  • Class Antibacterials; Monoclonal antibodies
  • Mechanism of Action CD14 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute lung injury
  • Phase I Motor neuron disease
  • Clinical Phase Unknown Adult respiratory distress syndrome
  • Discontinued Septic shock

Most Recent Events

  • 25 Apr 2018 Implicit Bioscience plans a phase II trial for Motor neuron disease in Australia (IV) in August 2018 (NCT03508453)
  • 22 Mar 2018 Implicit Bioscience plans a phase II study for Amyotrophic Lateral Sclerosis in USA in September 2018 (NCT03474263)
  • 01 Oct 2017 Phase-I clinical trials in Motor neuron disease in Australia (IV) (NCT03487263)
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