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Atibuclimab - Implicit Bioscience

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Drug Profile

Atibuclimab - Implicit Bioscience

Alternative Names: Anti-CD14 antibody; IC-14

Latest Information Update: 21 Aug 2024

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At a glance

  • Originator ICOS Corporation
  • Developer ICOS Corporation; Implicit Bioscience; National Institute of Allergy and Infectious Diseases; University of Washington; Vanderbilt University Medical Center
  • Class Anti-infectives; Anti-inflammatories; Antibacterials; Monoclonal antibodies
  • Mechanism of Action CD14 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute lung injury; SARS-CoV-2 acute respiratory disease
  • Phase I/II Cardiomyopathies
  • No development reported Motor neuron disease
  • Discontinued Septic shock

Most Recent Events

  • 21 Aug 2024 Implicit Bioscience plans phase I/II trial in Decompensated heart failure in US in October 2024 (IV) (NCT06556810)
  • 22 Jul 2024 Implicit Bioscience plans a phase II trial for Adult respiratory distress syndrome in USA (IV) in August 2024 (NCT06513949)
  • 29 Mar 2024 Phase-I/II clinical trials in Cardiomyopathies in USA (IV) (NCT06275893)

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