Sapacitabine - Cyclacel Pharmaceuticals

Drug Profile

Sapacitabine - Cyclacel Pharmaceuticals

Alternative Names: CS-682; CYC-682

Latest Information Update: 20 Apr 2018

Price : *
* Final gross price and currency may vary according to local VAT and billing address.
* Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. A link to download a PDF version of the drug profile will be included in your email receipt. Adis is an information provider. We do not sell or distribute the pharmaceutical compounds written about in this database.

At a glance

  • Originator Daiichi Sankyo Company; Hokkaido University; Kanazawa University
  • Developer Cyclacel Pharmaceuticals; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Arabinonucleosides; Small molecules
  • Mechanism of Action Antimetabolites; DNA-directed DNA polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myelodysplastic syndromes; Acute myeloid leukaemia
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Acute myeloid leukaemia
  • Phase II Chronic lymphocytic leukaemia; Myelodysplastic syndromes; Non-small cell lung cancer
  • Phase I/II Solid tumours
  • No development reported Ovarian cancer
  • Discontinued Cutaneous T cell lymphoma

Most Recent Events

  • 05 Apr 2018 Cyclacel Pharmaceuticals terminates a phase II trial due to accrual not met in Chronic lymphocytic leukaemia (Combination therapy, Second-line therapy or greater) in USA (PO) (NCT01253460)
  • 28 Mar 2018 Cyclacel Pharmaceuticals plans a phase Ib/II trial for Breast cancer (Combination therapy) (PO), in 2018
  • 21 Feb 2018 Cyclacel Pharmaceuticals has patent protection for pharmaceutical formulations of sapacitabine in USA
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top