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Tipapkinogene sovacivec - Transgene

Drug Profile

Tipapkinogene sovacivec - Transgene

Alternative Names: MVA-HPV-IL2 vaccine; R-3484; RG 3484; RO5217790; TG 4001

Latest Information Update: 16 Oct 2024

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At a glance

  • Originator Transgene
  • Developer EMD Serono Research & Development Institute; Merck & Co; Roche; Transgene
  • Class Antineoplastics; Cancer vaccines; Gene therapies; Immunotherapies; Papillomavirus vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Head and neck cancer; Oropharyngeal cancer
  • Phase I/II Anal cancer; Cervical cancer; Penile cancer; Vulvovaginal cancer
  • Discontinued Cervical intraepithelial neoplasia

Most Recent Events

  • 14 Oct 2024 Updated efficacy and adverse event data from a phase II trial in anogenital cancer released by Transgene
  • 05 Jun 2023 Efficacy data from a phase II trial in Anogenital cancer released by Transgene
  • 02 Jun 2023 Efficacy and immunogenicity data from phase-Ib/II trial in Anal cancer, Penile cancer, Vulvovaginal cancer and Cervical cancer presented at the 59th Annual Meeting of the American Society of Clinical Oncology (ASCO-2023)

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