Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

I-131-Apamistamab - Actinium Pharmaceuticals

Next Previous
Drug Profile

I-131-Apamistamab - Actinium Pharmaceuticals

Alternative Names: 131-I-labeled anti-CD45 antibody; 131-I-labeled BC8 antibody; 131I-BC8 (anti-CD45) antibody - Actinium Pharmaceuticals; Anti-CD45 monoclonal antibody-BC8-I-131; Anti-CD45 monoclonal antibody-I-131; BC 8; BC8-I-131 construct; I-131-BC8; I131-Apamistamab; Iodine I 131 Apamistamab; Iodine-131-apamistamab; Iomab-ACT; Iomab-B

Latest Information Update: 10 Sep 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Fred Hutchinson Cancer Research Center
  • Developer Actinium Pharmaceuticals; Fred Hutchinson Cancer Research Center; Memorial Sloan-Kettering Cancer Center
  • Class Antineoplastics; Immunoconjugates; Iodine radioisotopes; Monoclonal antibodies; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Acute myeloid leukaemia
  • Phase II Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase I/II Diffuse large B cell lymphoma
  • No development reported Hodgkin's disease; Non-Hodgkin's lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 10 Sep 2025 Actinium Pharmaceuticals plans a phase II/III trial for Acute myeloid leukaemia (Second-line therapy or greater, Combination therapy) (IV), in January 2026 (NCT07157514)
  • 25 Apr 2025 Phase-I/II clinical trials in Diffuse large B cell lymphoma (Second-line therapy or greater, Late-stage disease) in USA (IV) (NCT06768905)
  • 19 Mar 2025 Actinium Pharmaceuticals and the University of Texas Southwestern plans a CAR-T clinical trial for Hematological malignancies in the second half of 2025

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top