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Laquinimod - Active Biotech

Drug Profile

Laquinimod - Active Biotech

Alternative Names: ABR-215062; Laquinimod sodium; Nerventra; SAIK-MS; TV-5600

Latest Information Update: 15 Feb 2019

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At a glance

  • Originator Active Biotech
  • Developer Active Biotech; Icahn School of Medicine at Mount Sinai; National University of Singapore; Ruhr-University Bochum; Tel Aviv University; University College London; University of British Columbia
  • Class Anti-inflammatories; Neuropsychotherapeutics; Quinolones; Small molecules
  • Mechanism of Action Aryl hydrocarbon receptor agonists; Brain-derived neurotrophic factor expression stimulants; Immunomodulators; Neuron stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Huntington's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Multiple sclerosis
  • Phase II Huntington's disease
  • Discontinued Crohn's disease; Lupus nephritis; Systemic lupus erythematosus

Most Recent Events

  • 14 Feb 2019 Adverse events data from the phase II LEGATO-HD trial in Huntington's disease released by Active Biotech
  • 05 Sep 2018 Laquinimod is no longer licensed to Teva Pharmaceutical Industries worldwide
  • 24 Jun 2018 Biomarkers information updated
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