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Research programme: inhibitors of peptide deformylase and Mur pathway enzymes - Novartis/Pfizer

Drug Profile

Research programme: inhibitors of peptide deformylase and Mur pathway enzymes - Novartis/Pfizer

Alternative Names: 415; LBM-415; NVP-PDF-713; PDF7; VIC-104959; VRC 3852; VRC-3324; VRC-3375; VRC-4307; VRC-4887

Latest Information Update: 13 Mar 2008

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At a glance

  • Originator Novartis; Pfizer
  • Class Hydroxamic acids; Peptides
  • Mechanism of Action Cell wall inhibitors; Peptide deformylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Bacterial infections; Community-acquired pneumonia

Most Recent Events

  • 11 Sep 2005 Vicuron Pharmaceuticals has been acquired and merged into Pfizer
  • 04 Mar 2005 Suspended - Phase-I for Community-acquired pneumonia in USA (unspecified route)
  • 16 Nov 2004 Data presented at the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC-2004) have been added to the Bacterial infections antimicrobial activity, pharmacodynamics and pharmacokinetics section ,,,
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