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Research programme: cancer therapeutics - Endocyte

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Drug Profile

Research programme: cancer therapeutics - Endocyte

Alternative Names: CB-3717; EC 0531; EC 0651; EC 1812; EC 1868; EC 1977; EC-1744; EC1788; GARFTase inhibitors - Endocyte

Latest Information Update: 28 Dec 2021

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At a glance

  • Originator Endocyte
  • Class Depsipeptides; Doxorubicins; Drug conjugates; Folic acids; Oligopeptides; Small molecules; Taxanes
  • Mechanism of Action Folate receptor 1 antagonists; Phosphoribosylglycinamide formyltransferase inhibitors; Tubulin polymerisation inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Solid tumours

Highest Development Phases

  • No development reported Haematological malignancies; Solid tumours

Most Recent Events

  • 28 Dec 2021 No recent reports of development identified for preclinical development in Solid-tumours in USA
  • 28 Feb 2020 No recent reports of development identified for preclinical development in Haematological-malignancies in USA
  • 21 Dec 2018 Endocyte has been acquired by Novartis

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