Pelareorep - Oncolytics Biotech

Drug Profile

Pelareorep - Oncolytics Biotech

Alternative Names: PO-BB0209; REOLYSIN; Reosyn; Reovirus; Reovirus - Oncolytics Biotech; Reovirus anticancer; Reovirus antitumour; Reovirus Serotype 3 - Dearing Strain; Respiratory Enteric Orphan virus

Latest Information Update: 14 Jun 2018

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At a glance

  • Originator Oncolytics Biotech
  • Developer Mayo Clinic; National Cancer Institute (Canada); National Cancer Institute (USA); Oncolytics Biotech; University of Leeds; University of Southern California
  • Class Antineoplastics; Oncolytic viruses
  • Mechanism of Action Apoptosis stimulants; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Peritoneal cancer; Ovarian cancer; Gastric cancer; Pancreatic cancer; Fallopian tube cancer
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Head and neck cancer
  • Phase II Brain cancer; Breast cancer; Colorectal cancer; Lung cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Sarcoma
  • Phase I/II Glioma
  • Phase I Multiple myeloma
  • Preclinical Hepatocellular carcinoma; Viral hepatitis
  • No development reported Solid tumours

Most Recent Events

  • 01 Jun 2018 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 25 May 2018 Oncolytics Biotech and University of Southern California plan a clinical trial for Multiple myeloma (Combination therapy, Second-line therapy or greater) in the second half of 2018
  • 25 May 2018 Oncolytics Biotech enters into a collaboration with University of Southern California for a clinical trial in Multiple myeloma (Combination therapy, Second-line therapy or greater)
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