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Pelareorep - Oncolytics Biotech

Drug Profile

Pelareorep - Oncolytics Biotech

Alternative Names: AN-1004; PO-BB0209; REOLYSIN; Reosyn; Reovirus; Reovirus - Oncolytics Biotech; Reovirus anticancer; Reovirus antitumour; Reovirus Serotype 3 - Dearing Strain; Respiratory Enteric Orphan virus; Wild-type reovirus - Oncolytics Biotech

Latest Information Update: 20 Mar 2024

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At a glance

  • Originator Oncolytics Biotech
  • Developer Adlai Nortye; Canadian Cancer Society Research Institute; Mayo Clinic; National Cancer Institute (USA); Oncolytics Biotech; PrECOG; Roche; University of Leeds; University of Southern California
  • Class Antineoplastics; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Peritoneal cancer; Ovarian cancer; Gastric cancer; Pancreatic cancer; Fallopian tube cancer
  • New Molecular Entity No

Highest Development Phases

  • Phase III Breast cancer; Head and neck cancer
  • Phase II Brain cancer; Colorectal cancer; Fallopian tube cancer; Lung cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Prostate cancer; Sarcoma
  • Phase I/II Anal cancer; Glioma; Multiple myeloma
  • Preclinical Acute myeloid leukaemia
  • No development reported Glioblastoma; Liver cancer; Solid tumours

Most Recent Events

  • 07 Mar 2024 Oncolytics Biotech plans a registrational study in Pancreatic cancer (First line therapy) in 2024
  • 14 Feb 2024 Efficacy data from a phase I/II GOBLET trial in Pancreatic cancer released by Oncolytics Biotech
  • 13 Feb 2024 Pharmacodynamics data from a phase 0 AWARE-1 trial in Breast cancer presented at the 46th Annual San Antonio Breast Cancer Symposium (SABCS-2023)
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