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Pelareorep - Oncolytics Biotech

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Drug Profile

Pelareorep - Oncolytics Biotech

Alternative Names: AN-1004; PO-BB0209; REOLYSIN; Reosyn; Reovirus; Reovirus - Oncolytics Biotech; Reovirus anticancer; Reovirus antitumour; Reovirus Serotype 3 - Dearing Strain; Respiratory Enteric Orphan virus; Wild-type reovirus - Oncolytics Biotech

Latest Information Update: 02 Jul 2024

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At a glance

  • Originator Oncolytics Biotech
  • Developer Adlai Nortye; Canadian Cancer Society Research Institute; Mayo Clinic; National Cancer Institute (USA); Oncolytics Biotech; PrECOG; Roche; University of Leeds; University of Southern California
  • Class Antineoplastics; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Peritoneal cancer; Ovarian cancer; Gastric cancer; Pancreatic cancer; Fallopian tube cancer
  • New Molecular Entity No

Highest Development Phases

  • Phase III Breast cancer; Head and neck cancer
  • Phase II Brain cancer; Colorectal cancer; Fallopian tube cancer; Lung cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Prostate cancer; Sarcoma
  • Phase I/II Anal cancer; Glioma; Multiple myeloma
  • Preclinical Acute myeloid leukaemia
  • No development reported Glioblastoma; Liver cancer; Solid tumours

Most Recent Events

  • 27 Jun 2024 Oncolytics received productive feedback from Type C meeting with the USFDA
  • 09 May 2024 Oncolytics Biotech receives German regulatory and ethics approvals for Pelareorep in Pancreatic cancer
  • 07 May 2024 National Cancer Institute completes a phase-I trial in Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA (IV) (NCT02101944)
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