Drug Profile


Alternative Names: WX-UK1

Latest Information Update: 20 Nov 2017

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At a glance

  • Originator Wilex
  • Developer WILEX AG
  • Class Antineoplastics; Aromatic amino acids; Small molecules
  • Mechanism of Action Plasminogen activator inhibitor-1 inhibitors; Urokinase-type plasminogen activator inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 14 Apr 2014 Discontinued - Phase-I for Solid tumours in USA (IV)
  • 14 Apr 2014 Discontinued - Phase-I/II for Solid tumours in Germany (IV)
  • 25 Jan 2008 Interim efficacy, adverse event, pharmacokinetic and drug interactions data from a phase Ib trial in advanced solid tumours released by Wilex
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