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Romosozumab - Amgen/UCB

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Drug Profile

Romosozumab - Amgen/UCB

Alternative Names: AMG-785; Anti-sclerostin; Anti-sclerostin monoclonal antibody; CDP-7851; EVENITY; romosozumab-aqqg; Sclerostin Ab

Latest Information Update: 24 Jul 2024

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At a glance

  • Originator ChiroscienceGroup plc
  • Developer Amgen; UCB
  • Class Monoclonal antibodies; Osteoporosis therapies
  • Mechanism of Action SOST protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Male osteoporosis; Postmenopausal osteoporosis
  • Phase III Osteogenesis imperfecta; Osteoporosis
  • Discontinued Fracture

Most Recent Events

  • 10 Jun 2024 Amgen completes phase II trial in Osteoporosis in USA (SC) (NCT04708886)
  • 22 Apr 2024 Phase-III clinical trials in Osteogenesis imperfecta (In adolescents, In children) in Spain, Germany, Austria, Turkey, USA, Hungary (SC) (NCT05972551)
  • 22 Apr 2024 Phase-III clinical trials in Osteogenesis imperfecta (In children, In adolescents) in France, Switzerland, Slovakia, Poland, Japan, Canada, Belgium, Australia (SC) (NCT05972551)

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