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Conestat alfa - Pharming Group

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Drug Profile

Conestat alfa - Pharming Group

Alternative Names: Human C1 esterase inhibitor - Pharming; Recombinant human C1 esterase inhibitor - Pharming; rhC1INH; Rhucin; Ruconest

Latest Information Update: 28 May 2023

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At a glance

  • Originator Pharming Group NV
  • Class Anti-inflammatories; Antihypertensives; Complement C1 inactivator proteins; Recombinant proteins; Skin disorder therapies; Vascular disorder therapies
  • Mechanism of Action Complement C1r inhibitors; Complement C1s inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hereditary angioedema; Capillary leak syndrome; Delayed graft function
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hereditary angioedema
  • Phase II COVID 2019 infections; Stroke
  • No development reported Delayed graft function; Shock
  • Discontinued Acute kidney injury; Preeclampsia; Renal transplant rejection

Most Recent Events

  • 28 May 2023 No recent reports of development identified for clinical-Phase-Unknown development in COVID-2019-infections in Switzerland (IV, Infusion)
  • 04 Aug 2022 Discontinued - Phase-I/II for Preeclampsia (Prevention) in Australia (unspecified route) as per company decision
  • 04 Aug 2022 Discontinued - Phase-I/II for Preeclampsia (Prevention) in Netherlands (unspecified route) as per company decision

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