Conestat alfa - Pharming Group NV

Drug Profile

Conestat alfa - Pharming Group NV

Alternative Names: Human C1 esterase inhibitor - Pharming; Recombinant human C1 esterase inhibitor - Pharming; rhC1INH; Rhucin; Ruconest

Latest Information Update: 29 May 2018

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At a glance

  • Originator Pharming Group NV
  • Class Complement C1 inactivator proteins; Recombinant proteins; Vascular disorder therapies
  • Mechanism of Action Complement C1r inhibitors; Complement C1s inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hereditary angioedema; Delayed graft function; Capillary leak syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hereditary angioedema
  • Phase II Acute kidney injury
  • Preclinical Delayed graft function; Reperfusion injury
  • Discontinued Renal transplant rejection

Most Recent Events

  • 26 Jul 2018 Pharming Group plans to submit an application in 3Q 2018 to conduct a phase I/II trial in Preeclampsia in the 4Q 2018
  • 23 May 2018 Clinical trials in Hereditary angioedema (IM)
  • 23 May 2018 Clinical trials in Hereditary angioedema (SC)
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