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Eritoran - Eisai

Drug Profile

Eritoran - Eisai

Alternative Names: B-1287; E-5564; Eritoran tetrasodium

Latest Information Update: 13 Oct 2020

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At a glance

  • Originator Eisai Co Ltd
  • Class Disaccharides; Sugar phosphates
  • Mechanism of Action Endotoxin inhibitors; Lipid A inhibitors; Toll-like receptor 4 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Immunological disorders
  • Discontinued Reperfusion injury; Septic shock

Most Recent Events

  • 06 Oct 2020 Eisai enters into a joint research agreement with KAN Research Institute, National Center for Global Health and Medicine, Nagasaki University, Yokohama City University to develop therapeutics to prevent COVID-2019 infections
  • 03 Aug 2020 Phase-III clinical trials in Immunological disorders (suppression of cytokine storm in patients with COVID-2019 infections) in USA (IV) before August 2020 (Eisai pipeline, August 2020)
  • 03 Jul 2020 Eisai in collaboration with University of Pittsburgh Medical Center and The Global Coalition for Adaptive Research plans the REMAP-COVID clinical trial for COVID-2019 infections (Monotherapy, Combination therapy) in US and Japan
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