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JTV 519

Drug Profile

JTV 519

Alternative Names: JTV-519; K201 - Merck; K201 - Sequel

Latest Information Update: 19 Aug 2015

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At a glance

  • Originator Aetas Pharma; Japan Tobacco
  • Developer Sequel Pharmaceuticals
  • Class Small molecules; Thiazepines
  • Mechanism of Action Calcium channel antagonists; Potassium channel antagonists; Protein kinase C stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Atrial fibrillation; Cancer; Heart failure; Myocardial infarction

Most Recent Events

  • 13 May 2011 Sequel Pharmaceuticals terminates phase II trial in Atrial fibrillation in Denmark and Israel (NCT01259622)
  • 13 May 2011 Sequel Pharmaceuticals terminates phase II trial in Atrial fibrillation in US and EU (NCT01067833)
  • 12 Sep 2007 NovaCardia has been acquired by Merck and Co
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