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Pamrevlumab - Kyntra Bio

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Drug Profile

Pamrevlumab - Kyntra Bio

Alternative Names: Anti-CTGF antibody - Kyntra Bio; FG-3019

Latest Information Update: 28 Jan 2026

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At a glance

  • Originator FibroGen
  • Developer Kyntra Bio
  • Class Antifibrotics; Antineoplastics; Antivirals; Cardiovascular therapies; Immunotherapies; Monoclonal antibodies; Urologics
  • Mechanism of Action Connective tissue growth factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy; Pancreatic cancer; Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued COVID 2019 infections; Diabetic cardiomyopathy; Diabetic nephropathies; Diabetic neuropathies; Duchenne muscular dystrophy; Glioblastoma; Glomerulonephritis; Hepatic fibrosis; Idiopathic pulmonary fibrosis; Pancreatic cancer

Most Recent Events

  • 07 Jan 2026 FibroGen is now called Kyntra Bio
  • 05 Feb 2025 Pancreatic Cancer Action Network completes the Phase-II/III clinical trials in Pancreatic cancer (Second-line therapy or greater, First-line therapy, Metastatic disease, Combination therapy) in USA (IV) (NCT04229004)
  • 23 Jan 2025 Efficacy and adverse events data from the phase III LAPIS trial in Pancreatic cancer presented at the 2025 Gastrointestinal Cancers Symposium (ASCO-GCS-2025)

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