Pamrevlumab - FibroGen

Drug Profile

Pamrevlumab - FibroGen

Alternative Names: Anti-CTGF antibody; FG-3019

Latest Information Update: 27 Mar 2018

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At a glance

  • Originator FibroGen
  • Class Antifibrotics; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Connective tissue growth factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer; Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Duchenne muscular dystrophy; Idiopathic pulmonary fibrosis; Pancreatic cancer
  • Discontinued Diabetic cardiomyopathy; Diabetic nephropathies; Diabetic neuropathies; Glioblastoma; Glomerulonephritis; Hepatic fibrosis

Most Recent Events

  • 27 Mar 2018 Discontinued - Phase-II for Hepatic fibrosis in Thailand and Hong Kong (IV)
  • 26 Mar 2018 Discontinued - Phase-I for Glomerulonephritis in USA (IV)
  • 26 Mar 2018 Discontinued - Preclinical for Glioblastoma in Germany (Parenteral)
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