Finafloxacin - MerLion Pharmaceuticals

Drug Profile

Finafloxacin - MerLion Pharmaceuticals

Alternative Names: AL-60371; BY-377; EXE 844; EXE 844b; Finafloxacin hydrochloride; Gastrochinolon; Gastroquinolone; Xtoro

Latest Information Update: 08 Aug 2018

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At a glance

  • Originator Bayer
  • Developer Alcon; MerLion Pharmaceuticals
  • Class Antibacterials; Eye disorder therapies; Fluoroquinolones; Small molecules
  • Mechanism of Action DNA gyrase inhibitors; DNA topoisomerase IV inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Otitis externa
  • Phase II Helicobacter infections; Pyelonephritis; Urinary tract infections
  • Phase I Otitis media
  • No development reported Bacterial infections; Respiratory tract infections

Most Recent Events

  • 31 Jul 2018 MerLion regains global rights to finafloxacin after termination of licensing deal between Alcon and MerLion
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Bacterial-infections(In volunteers) in United Kingdom (IV, Infusion)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Helicobacter-infections(In volunteers) in Switzerland (PO, Tablet)
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