MDCO 216
Alternative Names: AIM; ApoA1 Milano; ESP-24217; ET-216; ETC-216; MDCO-216; r-ApoA-I Milano; rApoA-IM; rApoA-IM protein (dimer)Latest Information Update: 07 Nov 2021
At a glance
- Originator Pfizer
- Developer Esperion Therapeutics; The Medicines Company
- Class Ischaemic heart disorder therapies; Phosphatidylcholines; Phospholipids
- Mechanism of Action Apolipoprotein A-I stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Acute coronary syndromes; Coronary artery disease; Coronary artery restenosis
Most Recent Events
- 06 Jan 2020 The Medicines Company has been acquired by Novartis
- 07 Nov 2016 Discontinued - Phase-I for Coronary artery disease in USA due to lack of effficacy (IV)
- 07 Nov 2016 Discontinued - Phase-II for Acute coronary syndromes in Canada, Czech Republic, Netherlands, Poland, Hungary and USA due to lack of effficacy (IV)