Polyphenon E - Medigene

Drug Profile

Polyphenon E - Medigene

Alternative Names: Polyphenon E; Polyphenon E (green tea extract); Polyphenon E Ointment; SB 03; Sinecatechins; Sinecatechins 10% ointment; Sinecatechins 15%; Veregen

Latest Information Update: 08 Dec 2017

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At a glance

  • Originator Mitsui Norin; Polyphenon Pharma
  • Developer Maastricht University; MediGene AG; Polyphenon Pharma; SynCore Biotechnology; Triton Pharma; Will-Pharma
  • Class Antineoplastics; Antivirals; Catechins; Herbal medicines
  • Mechanism of Action Antioxidants; Immunostimulants; Viral fusion protein inhibitors; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic lymphocytic leukaemia
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Genital warts
  • Phase II/III Basal cell cancer
  • Phase II Prostatic intraepithelial neoplasia
  • No development reported Bladder cancer
  • Discontinued Actinic keratosis; Angina pectoris; Chronic lymphocytic leukaemia

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 05 Dec 2017 Polyphenon E licensed to Fougera Pharmaceuticals in USA
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Bladder-cancer in USA (PO)
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