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Ticagrelor - AstraZeneca

Drug Profile

Ticagrelor - AstraZeneca

Alternative Names: AR-C-126532; AZD-6140; Brilinta; Brilique

Latest Information Update: 25 Sep 2019

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; The Medicines Company; Uppsala University; Vanderbilt University
  • Class Antianaemics; Antibacterials; Antithrombotics; Cardiovascular therapies; Cyclopropanes; Fluorobenzenes; Purine nucleosides; Ribonucleosides; Small molecules; Vascular disorder therapies
  • Mechanism of Action Platelet ADP receptor antagonists; Purinoceptor P2Y12 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute coronary syndromes
  • Phase III Cardiovascular disorders; Sickle cell anaemia; Stroke
  • Phase II Abdominal aortic aneurysm; Community-acquired pneumonia; Coronary artery disease
  • Discontinued Peripheral arterial disorders

Most Recent Events

  • 02 Sep 2019 Efficacy and adverse events data from the phase III THEMIS trial in Cardiovascular disorders released by AstraZeneca
  • 26 Aug 2019 Region Skane in collaboration with AstraZeneca plans the phase III AUGEAS trial for Coronary Artery Disease in diabetes mellitus patients (NCT04069234)
  • 07 May 2019 AstraZeneca completes the phase I HESTIA4 trial in Sickle cell anaemia (In infants) in United Kingdom, Lebanon, Spain, Kenya, Italy, Belgium (PO) (NCT03492931)
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