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Ticagrelor - AstraZeneca

Drug Profile

Ticagrelor - AstraZeneca

Alternative Names: AR-C-126532; AZD-6140; Brilinta; Brilique

Latest Information Update: 10 Dec 2018

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; The Medicines Company; Uppsala University; Vanderbilt University
  • Class Antianaemics; Antibacterials; Antithrombotics; Cardiovascular therapies; Cyclopropanes; Fluorobenzenes; Purine nucleosides; Ribonucleosides; Small molecules; Vascular disorder therapies
  • Mechanism of Action Platelet ADP receptor antagonists; Purinoceptor P2Y12 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute coronary syndromes
  • Phase III Cardiovascular disorders; Sickle cell anaemia; Stroke
  • Phase II Abdominal aortic aneurysm; Community-acquired pneumonia; Coronary artery disease
  • Discontinued Peripheral arterial disorders

Most Recent Events

  • 10 Nov 2018 Efficay and adverse events data from the phase III PEGASUS-TIMI 54 trial in Ischemic heart disease (IHD) presented at the 91st Annual Scientific Sessions of the American Heart Association (AHA-2018)
  • 26 Sep 2018 Phase-III clinical trials in Sickle cell anaemia (In children, In adolescents) in Spain, Belgium (PO) (NCT03615924)
  • 25 Aug 2018 Additional adverse events data from the phase III PLATO trial in Acute coronary syndromes presented at the Annual Congress of the European Society of Cardiology (ESC-2018)
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