Ticagrelor - AstraZeneca

Drug Profile

Ticagrelor - AstraZeneca

Alternative Names: AR-C-126532; AZD-6140; Brilinta; Brilique

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; The Medicines Company; Uppsala University; Vanderbilt University
  • Class Antithrombotics; Cyclopropanes; Fluorobenzenes; Purine nucleosides; Ribonucleosides; Small molecules
  • Mechanism of Action Platelet ADP receptor antagonists; Purinoceptor P2Y12 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute coronary syndromes
  • Phase III Cardiovascular disorders; Stroke
  • Phase II Abdominal aortic aneurysm; Community-acquired pneumonia; Coronary artery disease; Sickle cell anaemia
  • Discontinued Peripheral arterial disorders

Most Recent Events

  • 11 Mar 2018 Initial efficacy and adverse events data from the phase III TREAT trial in Acute coronary syndromes released by AstraZeneca
  • 07 Feb 2018 Pre-specified sub-analysis of efficacy and adverse events data from a phase III PEGASUS-TIMI 54 trial in Acute coronary syndromes released by AstraZeneca
  • 02 Feb 2018 AstraZeneca announces intention to submit regulatory applications for Stroke (Acute ischaemic stroke or transient ischaemic attack) in USA, European Union, Japan and China in 2020
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